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Not all reflux comes from low stomach acid. Here’s why betaine HCl worries me as a dietitian. 🧪 GERD is mostly a pressure and containment problem: transient LES relaxations, slow esophageal clearance, and mucosal barrier breakdown (Bertin et al., Digestion, 2025). Betaine HCl is supplemental hydrochloric acid. Pepsin, the enzyme that damages your esophagus and throat, needs acid to switch on, and tissue-bound pepsin can be reactivated by acid from any source (Koufman and Johnston, 2012). If you
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