Rapid-acting insulin • Humalog → Lispro • Novolog → Aspart • Apidra → Glulisine Short-acting insulin • Humulin R / Novolin R → Regular insulin Intermediate-acting insulin • Humulin N / Novolin N → NPH Long-acting insulin • Lantus → Glargine • Levemir → Detemir Ultra-long acting insulin This is now considered a separate class in modern classifications: • Tresiba → Degludec (duration >42 hours) • Toujeo → Glargine U-300 (longer & flatter than Lantus) Premixed insulin • 70/30 (NPH Regular) • 75/25

Insulin is administered by the subcutaneous route. Why is it not administered by the oral route? Insulin is a polypeptide so it is susceptible to degradation in GIT, hence it is administered through s/c route to show its effects. Insulin has different types based upon their onset and duration of action. *1) Rapid Acting Insulin:* eg; Lispro, Aspart, Glulisine *2) Short Acting Insulin:* eg; Regular insulin *3) Intermediate Acting Insulin:* eg; NPH (Neutral Protamine Hagedorn) *4) Long Acting Insu