Mar 19, 2021 · We found DNER as a potential genetic risk confirmed by 2 independent GWAS. Additionally, DNER gene expression was upregulated in smoker patients analysed in the GWAS …

Expression of DNER in glioblastoma stem-like cells inhibits formation of neurospheres in vitro, while in vivo it induces differentiation and inhibits growth of xenografts, thus acting as a tumor suppressor.

We demonstrate that DNER regulates enteric neural crest cell proliferation, migration, and differentiation via the Notch signaling

DNER is a transmembrane protein and a proposed Notch ligand. DNER has been implicated in neuron-glia development and cell-cell interactions. Studies herein demonstrate that DNER is expressed in b …

Here, we identified Delta/Notch-like EGF-related receptor (DNER), a neuron-specific transmembrane protein, as a previously unknown ligand of Notch during cellular morphogenesis of Bergmann glia...

stibular system, we find that DNER is expressed in hair cells and vestibular ganglion neurons during development and in adults. To investigate whether DNER plays a fu. nal role in the inner ear, …

Delta/Notch-like EGF-related receptor (DNER) is a transmembrane protein primarily found in the central nervous system (CNS) and specifically, found abundantly in Purkinje neurons of the cerebellum[1].