Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

The San Francisco 49ers and Buffalo Bills are set to face-off in the Week 13 edition of Sunday Night Football. Before the season began, this matchup was circled ...

The Toronto Raptors open a seven-game homestand Sunday night with a chance to avenge a loss to the Miami Heat in a return match.

Areas south of Highway 20 are a few degrees warmer, but still very cold in the double digits to low teens. Wind chill values ...

Head Coach Sean Payton discusses Denver's prime-time matchup in Week 13, game-planning for each opponent and more.

LEXINGTON, Ky. (WKYT) - Saturday and Sunday are FIRST ALERT WEATHER DAYS as a light snowfall is expected Saturday night into ...

The 49ers are expected to get Brock Purdy back for Sunday's game, and Brian Robinson Jr. (ankle) is set to go for the ...

The first big snow of the season has the potential to bury towns in New York along lakes Erie and Ontario during a hectic holiday travel and shopping weekend.

Sunday is the first day of December and the first day of meteorological winter and it will certainly feel like it. Highs will ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

Low temperatures plummet into the upper-20s and lower-30s by Sunday morning. Remember, protect your pets and plants.

Clouds will be moving in overnight and should keep our low temperature from dipping any farther than 28 degrees. Those clouds ...