The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

Head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, DL Nick Bosa and others and discussed the team's ...

Brock Purdy is expected to return Sunday night against the Bills, but offensive tackle Trent Williams, defensive end Nick ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

The 49ers won't have their best pass rusher when they face the Bills on Sunday. Nick Bosa will miss his second game in a row with an oblique injury ...

San Francisco 49ers defensive end Nick Bosa (97) celebrates after sacking Tampa Bay Buccaneers quarterback Baker Mayfield ...

San Francisco will be without two of their biggest stars again, but should have their talented passer back in the saddle.

The San Francisco 49ers are on the verge of falling out of contention for a playoff spot in the NFC after consecutive losses ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

San Francisco 49ers defensive end Nick Bosa (hip) and offensive tackle Trent Williams (ankle) will not suit up in Week 13 to face the Buffalo Bills, according to Eric Branch of the San Francisco ...