Dane -- who shot to fame amid six seasons on the hit ABC drama "Grey's Anatomy," where he played Dr. Mark Sloan, affectionately known as "McSteamy" -- said his symptoms began over one year ago, when he began to experience weakness in his right hand.

Eric Dane, an actor best known for playing Dr. Mark Sloan, aka "McSteamy," on "Grey's Anatomy," discussed his health challenges after being diagnosed with ALS.

He emphasized his perseverance moving forward, saying, “I’m fighting as much as I can,” though he admitted, “There’s so much about it that is out of my control.”