Preclinical data demonstrate BBO-10203 blocks RAS-mediated activation of PI3Kα, strongly inhibits pAKT signaling in tumor cells without inducing hyperglycemia, and shows robust anti-tumor activity ...

Data highlights the ability of Akari’s Trop2 ADC, AKTX-101, to kill K-Ras G12V mutated cancer cell lines in preclinical models, potentially addressing one of the most lethal cancers with the lowest ...

TAMPA, Fla. and LONDON, Dec. 09, 2025 (GLOBE NEWSWIRE) -- Akari Therapeutics, Plc (Nasdaq: AKTX), an oncology biotechnology company developing novel payload antibody drug conjugates (ADCs), today ...

CHARLOTTE — Thermal Road in southeast Charlotte is closed for culvert improvements, with the closure expected to last until Aug. 21, 2026. The road closure affects the section between Ramath Drive and ...

Risks and Challenges While Revolution Medicines’ clinical data appears promising, investors should note several risks. The increased R&D spending could pressure financial results if new treatments ...

The audio version of this article is generated by AI-based technology. Mispronunciations can occur. We are working with our partners to continually review and improve the results. A pair of culverts ...

Vividion Therapeutics, Inc. (Vividion), a clinical-stage biopharmaceutical company, and a wholly owned and independently operated subsidiary of Bayer AG, today announced the publication of a ...

State 42 will close to thru-traffic in and around Forestville for about a month starting Oct. 6 for a Wisconsin Department of Transportation project to replace two deteriorated concrete box culverts ...

Bain Capital agreed to sell its data centers in China to Shenzhen Dongyangguang Industry Co. in a transaction valued at about $4 billion. Shenzhen Dongyangguang, the parent of Shanghai-listed ...

MEDINA, N.Y. – There are lots of ways to go over the Erie Canal but there is just one that lets you cross underneath. This is the Medina Culvert — a stone arch tunnel built in 1823. It is the only ...

As AI workloads scale and data center operations become increasingly complex, it is critical to keep the infrastructure up and running. Total Cost of Ownership (TCO) is a key metric that includes not ...