IEEE

DHAG-DTA: Dynamic Hierarchical Affinity Graph Model for Drug-Target Binding Affinity Prediction

Abstract: Computational methods for predicting drug-target binding affinity (DTA) are critical for large-scale screening of prospective therapeutic compounds during drug discovery. Deep neural ...
C&EN

Combination of Autodisplay and Dynamic Pharmacophore Modeling Reveals New Insights into Cyclic Nucleotide Binding in Hyperpolarization-Activated and Cyclic Nucleotide-Gated Ion ...

Hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels play a critical role in regulating neuronal and cardiac rhythmicity, with their function being modulated by cyclic nucleotide ...
Business Wire

Depixus Announces Strategic Collaboration With Daiichi Sankyo to Use MAGNA™ Technology to Accelerate RNA-targeted Drug Discovery

PARIS--(BUSINESS WIRE)--Interactomics pioneer Depixus has entered a collaboration with Daiichi Sankyo to use their novel MAGNA™ technology to accelerate the Japanese healthcare leader’s RNA-targeted ...
C&EN

Unexpected Mechanism and Inhibition Effect for Nonspecific Amplification Involving Dynamic Binding of Primers with Background DNA

State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, Qingdao 266404, China State Key Laboratory of Marine Food ...
InfoWorld

Intro to HTMX: Dynamic HTML without JavaScript

HTMX is the HTML extension syntax that replaces JavaScript with simple markup. It could change the course of web development. HTMX lets you use an extended HTML syntax instead of JavaScript to achieve ...
IEEE

TrGPCR: GPCR–Ligand Binding Affinity Prediction Based on Dynamic Deep Transfer Learning

Abstract: Predicting G protein–coupled receptor (GPCR) –ligand binding affinity plays a crucial role in drug development. However, determining GPCR–ligand binding affinities is time-consuming and ...
GitHub

Dynamically changing Row and Column values of pivottable.js output chart

I am hoping this is the correct platform to post this. I have an asp .net app which is used as a reporting platform. Currently, I have managed to bind the pivot table and chart (pivottable.js) to a ...
Scientific Research Publishing

White, D., Honoré, S. and Hubert, F. (2017) Exploring the Effect of End-Binding Proteins and Microtubule Targeting Chemotherapy Drugs on Microtubule Dynamic Instability ...

ABSTRACT: In this paper, we describe an algorithm that performs automatic detection and tracking of astral microtubules in fluorescence confocal images. This sub-population of microtubules only exists ...