Heterologous prime-boost immunization strategies in general establish higher frequencies of antigen-specific T lymphocytes than homologous prime-boost protocols or single immunizations. We developed ...

Many viruses undergo large-scale conformational changes during their life cycles. Blocking the transition from one stage of the life cycle to the next is an attractive strategy for the development of ...

Neste trabalho, analisa-se o risco de emergência dos alphavirus Mayaro, da encefalite eqüina venezuelana, da encefalite eqüina do leste e Chikungunya, dos flavivirus, da febre amarela, Rocio, da ...