The San Francisco 49ers face a critical juncture in their season as injuries to star players Nick Bosa and Brock Purdy ...

The Week 12 injury report is an extremely demoralizing one for the San Francisco 49ers. First, it was Brock Purdy who was ruled out with a shoulder injury. Now, ...

On C/G Josh Myers playing with the bad wrist: Josh is a warrior, man. He plays through it. He's banged up. We all are. It's ...

Kyle Shanahan on Brandon Allen: "He’s done a really good job since he’s been here. Been here two years now and guys believe in him.” ...

The division rivalries continue into Week 12 with several high-stakes games on Sunday. Then, Sunday Night Football brings an NFC showdown between the Eagles and Rams. Check out the five can't-miss ...

In Sporting News' latest weekly game picks and predictions against the spread for Week 12, the Ravens take home another ...

San Francisco 49ers head coach Kyle Shanahan spoke to reporters ahead of Wednesday's practice as the team prepares for its ...

The star pass rusher would be in danger of missing his first game of the season Sunday against the Packers if he's unable to practice in at least a limited capacity Thursday and/or Friday.

For the first time all season, there's a new No. 1 in our NFL power rankings after the Chiefs lost to the Bills. But how far does Kansas City fall?

Meanwhile, Harbaugh is in Los Angeles, coaching the Chargers to a 7-3 record, with quarterback Justin Herbert looking like a ...

Three reasons to by stock in the Seattle Seahawks after their win against San Francisco, and two reasons not to.

Nick Bosa's oblique injury weakened the 49ers' defense, helping Seattle clinch a last-second win with Geno Smith's touchdown.