Manchester City could be without three players for Sunday’s gigantic showdown with Arsenal including talisman Kevin De Bruyne.

LONDON, United Kingdom (AFP) — Arsenal have to show they are ready to topple Premier League champions Manchester City in Sunday’s top-of-the-table clash between the title favourites, according to Gunners’ boss Mikel Arteta.

Arsenal wrap up a gruelling week on the road with a third straight away game when they face champions Manchester City in the Premier League on Sunday and manager Mikel Arteta said his squad had been preparing for the clash since preseason.

Manchester City are set to be without Kevin De Bruyne for their mammoth meeting with Arsenal in the Premier League on Sunday afternoon in a huge blow.The Belgian international was withdrawn at the

Manchester City manager Pep Guardiola refused to rule Kevin De Bruyne out of Sunday's clash with Arsenal, saying he could yet be involved despite picking up an injury on Wednesday.

The latest injury news from Manchester City before their Premier League showdown against title rivals Arsenal at the Etihad Stadium on Sunday afternoon (4.30pm).

The Belgium playmaker was forced off at half-time during City's Champions League draw with Inter Milan on Wednesday with a muscular problem. Manager Pep Guardiola is hopeful De Bruyne will still be able to line up for the Premier League champions against last seasonâ™s runners-up at the Etihad Stadium.

Kevin De Bruyne suffered an injury during Manchester City's UEFA Champions League draw against Inter Milan. Although it is not a serious setback, he is a doubt to face Arsenal.

Manchester City have discovered the extent of Kevin De Bruyne's injury ahead of their blockbuster Arsenal clash.