Traffic is severely backed up in the southbound lanes of I-81 in Franklin County due to a crash in Washington County, Md.

Portions of Interstate 81 were closed Monday morning in Augusta County following the crash of a tanker truck, authorities ...

The New York State Department of Transportation (NYSDOT) is letting drivers know of lane closures on Interstate 81 southbound ...

A disabled tractor-trailer is blocking traffic on Interstate 81, causing a severe backup in the northbound lanes.

Police closed the Main Avenue exit and on-ramps for I-81 South after a pedestrian was struck Wednesday morning.

A tractor-trailer accident on Interstate 81 on Monday prompted hazmat teams to clear the scene before anyone could drive through the area again safely.

Crews responded to the collision in the 3400 block of Black Gap Road/Route 997 in Greene Township around 10:20 a.m. The scene is just west of the Interstate 81 southbound ramps. The crash is blocking ...

State Police say Manuel De Jesus Ascencio Castro, 32, led police on a high-speed chase on the highway with a woman and three ...

A tractor-trailer driver died as the result of a crash on Interstate 81 in Montgomery County on Sunday, according to state ...

A pickup truck was traveling south on Interstate 81. The driver lost control and the truck went off the road, through a guide ...