EMBO Press

From microscopes to maps: enabling a new era of open and reproducible data sharing in intravital imaging

In this issue of The EMBO Journal, Pizzagalli and colleagues present proof-of-principle analyses of immune cell motility ...
EurekAlert!

An interpretable machine learning model for predicting 5‐year survival in breast cancer based on integration of proteomics and clinical data

Breast cancer is a highly heterogeneous malignancy among women worldwide. Traditional prognostic models relying solely on ...
SBCNews

BETBY activates two major e-Sim launches

Sportsbook supplier BETBY has strengthened its eSports platform with the addition of two new e-Sim disciplines.
SBCNews

Spelinspektionen fines IF Björklöven over licence obligation deficiencies

Sweden’s gambling regulator, Spelinspektionen, has fined ice hockey team IF Björklöven with SEK 25,000 (£2k). IF Björklöven ...
eLife

Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

This study investigates the folding and unfolding behavior of the doubly knotted protein TrmD-Tm1570, providing insight into the molecular mechanisms underlying protein knotting. The findings reveal ...
eLife

Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

Kinesin-1 is a dynamic heterotetrameric assembly of two heavy and two light chains (KHC and KLC) that mediates microtubule-based intracellular transport of many different cargoes. The complex adopts a ...