epinephrine and glucagon rapidly increase the amount of active phosphorylase in pre-incubated liver slices 1,2. In order to study the nature of the change in the phosphorylase molecule ...

Ascletis Pharma has reported positive topline outcomes from its US Phase Ia single ascending dose (SAD) study of the oral tablet, ASC30, in obese individuals. The study, which involved 40 obese ...

Injecting old mice with an RNA molecule seems to reverse some signs of ageing — helping them to live longer, regrow hair and maintain their physical and mental abilities. Ageing studies in five ...

Veiga-Fernandes and colleagues reported on their findings in Science, in a paper titled “Neuronal-ILC2 interactions regulate pancreatic glucagon and glucose homeostasis.” In their report the ...

State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province ...

Attempts to design small molecule therapies directed to this cytokine have not led to approved products yet. Here we report the discovery and development of a potent small molecule inhibitor of TNF ...