The 49ers won't have their best pass rusher when they face the Bills on Sunday. Nick Bosa will miss his second game in a row with an oblique injury ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

Matt Maiocco shares the latest practice report for the San Francisco 49ers and Buffalo Bills ahead of their Week 13 game on ...

Bosa (hip/oblique) will not practice Wednesday, Nick Wagoner of ESPN.com reports. Bosa missed last Sunday's loss to the Packers after he was injured in the Week 11 loss to the Seahawks. Sam Okuayinonu ...

San Francisco 49ers defensive end Nick Bosa (hip/oblique) was pulled from his team's Week 11 loss to the Seattle Seahawks due ...

The San Francisco 49ers’ season is on the ropes after a 38-10 loss to the Green Bay Packers on Sunday at Lambeau Field. San ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

Ten games into their season, the San Francisco 49ers wound up back at .500 for the fifth time as their schedule moves into an ...