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For adults ages 27 to 45, vaccinating against human papillomavirus (HPV) is costlier and less effective than vaccinating younger people to prevent HPV-related cancers (Ann Intern Med 2024 Nov 26 [Epub ...
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Major Finding: FastGlioma, an AI-based visual model, rapidly scores the degree of glioma infiltration in surgical samples. Concept: This approach represents a rapid, label-free surgical adjunct that ...
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Treatment with eflornithine led to clinically meaningful improvements in overall survival (OS) and progression-free survival (PFS) for patients with recurrent grade 3 IDH-mutant astrocytoma, an ...
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Chimeric antigen receptors (CAR) enable MHC-independence but do not recreate the precise molecular regulation induced by T-cell receptor (TCR) complexes. In an effort to engage endogenous TCR circuits ...
Major Finding: A dual function supracluster was engineered to increase radiosensitivity and antitumor immunity. Concept: Gold supraclusters carrying siRNA against LGALS1 (galectin-1) reshaped the ...
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1Fred Hutchinson Cancer Center, Seattle, WA.
“We look forward to achieving our goal of being a catalyst for the next big discovery.” ...