Our college football experts predict, pick and preview the NC State Wolfpack vs. Clemson Tigers game, with kickoff time, TV channel and spread.

Both teams are preparing for their first conference matchup of 2024, with the Wolfpack winning two of the last three meetings since 2021, including a 24-17 victory last year. However, oddsmakers favor Clemson, and USA TODAY Sports’ six-member panel unanimously predicted a Tiger win.

Clemson and NC State face off in this ACC opener on Saturday in college football’s Week 4 action. Here’s what you need to know, along with our updated game pred

Pregame analysis and predictions of the NC State Wolfpack vs. Clemson Tigers NCAAF game to be played on September 21, 2024 on ESPN.

CLEMSON, S.C. — N.C. State coach Dave Doeren said he won’t let his team’s season be defined by one bad early loss to Tennessee. He sure sounds a lot like his Clemson counterpart, Dabo Swinney, after the Tigers were manhandled by Georgia to start the season.

Clemson (1-1) was picked to finish second in the ACC race and N.C. State (2-1) was picked fourth, making this a key early matchup in the league title chase in the ACC opener for both teams. N.C. State hasn't won at Clemson since 2002 with Philip Rivers at quarterback,