Human cells - like those of many other organisms - have developed mechanisms to protect us from cancer. Healthy cells produce a suite of molecules that stop harmful mutations from accumulating. The ...

Negative feedback is a universal control mechanism that lets a system's output throttle its input. If an engine revs up, negative feedback tapers its power source. But if the engine slows down, it ...

The HiChIP protocol, unlike assays such as ChIA-PET and ChIP-seq, involves a restriction enzyme. This results in a read-density landscape that is biased by proximity to restriction sites (Fig. 1b), ...