Osteogenesis imperfecta (OI), also known as brittle bone disease, is a rare genetic disease affecting the connective tissue and bones. In this disease, bones become extremely fragile and break or ...

The Rodeo Telescopic Nail is an innovative device indicated to surgically treat deformities or fractures in patients suffering from osteogenesis imperfecta (OI). The nail implant serves to stabilize ...

What Is Brittle Bone Disease? Brittle bone disease, also called osteogenesis imperfecta, is a genetic connective tissue disorder that is preset at birth and lasts for life. It causes fragile bones ...

Trial results show setrusumab reduces the incidence of fracture and increases bone density and formation. The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to ...

Maybe you heard about it after watching the Samuel L. Jackson movie "Unbreakable." Or maybe after binging Season 11 of "Grey's Anatomy." Or maybe the words "osteogenesis imperfecta," or "OI," don't ...

Please provide your email address to receive an email when new articles are posted on . The classification system associated with prenatally diagnosed osteogenesis imperfecta may be outdated. Modern ...

Adityakumar Yadav, 7, loves to play and run around. However, he slipped from a staircase in his school, and fractured his left leg for the seventh time. The Chattisgarh boy suffers from Osteogenesis ...

Osteogenesis imperfecta (OI) is a heterogeneous group of genetic disorders that affect connective tissue integrity. The hallmark of OI is bone fragility, although other manifestations, which include ...

Could you describe the events leading up to your diagnosis? When I was born, both my femurs were fractured. But, I had normal height and weight, so the doctors struggled to find out what was going on.

Classic osteogenesis imperfecta, an autosomal dominant disorder associated with osteoporosis and bone fragility, is caused by mutations in the genes for type I collagen. A recessive form of the ...