Chemical modification of proteins enables the development of proteins with novel functions and properties and has industrial and pharmacological applications. Modified proteins can exhibit improved ...
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ALS breakthrough: Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).
Itaconate, an endogenous mitochondrial metabolite produced by the enzyme aconitate decarboxylase 1 (ACOD1), has emerged as a central regulator of ...
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...
"For histones, the time window for modifications is incredibly tight because their protein chains are very short," explains first author Denis Yudin, a doctoral student in Nenad Ban's lab. "NAC ...
Scientists at the Baylor College of Medicine say they have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called ...
Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...
Protein palmitoylation and lipid modifications are essential postātranslational processes that regulate protein localisation, stability and function by the covalent attachment of fatty acid chains.
A research team has developed an innovative technique that enables precise modification of specific proteins within complex biological environments. A research team led by Professor Seung Soo Oh and ...
(Nanowerk Spotlight) Protein-based nanomaterials that respond to light are emerging as candidates for integrating biological compatibility with programmable electronic behavior. Their appeal lies in ...
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