We propose that the forward and reverse halves of a flash-induced protein-protein electron transfer (ET) photocycle should exhibit differential responses to dynamic interconversion of configurations ...
A mechanistic understanding of the cell requires the structural characterization of the thousands of its constituent biological assemblies 1. So far, conventional approaches have provided a valuable ...
A USC-led international team of scientists has found the precise shape of a key player in human metabolism, which could lead the way to better treatments for obesity and other metabolic disease. For ...
Scientists report two new cryo-EM structures representing the pre- and postfusion conformations of the full-length SARS-CoV-2 spike (S) protein, an essential viral component responsible for host cell ...
Scientists report two new cryo-EM structures representing the pre- and postfusion conformations of the full-length SARS-CoV-2 spike (S) protein, an essential viral component responsible for host cell ...
The active sensing site of GPR4 is made up of histidine residues (Figure 1). 2 This is of particular interest, given that the dissociation constant representing the dissociation of histidine protons ...
With the continuing spread of the COVID-19 pandemic, researchers are stepping up their search for effective pharmaceutical interventions. This has taken various forms, including computational modeling ...