Every time we feel a gentle tap on the skin, specialized nerve cells convert that physical force into an electrical signal ...

A new study from Scripps Research reveals how a key touch-sensing protein detects mechanical forces with remarkable precision. Each time something lightly presses against your skin, specialized sensor ...

Urinary reflexes have been thought to depend on mechanically sensitive ion channels. But the identities of these channels—and the identities of the cells these channels sensitize—have been unclear.

The researchers think topical application of PIEZO2 blockers could be beneficial for patients suffering from neuropathic pain. If you've ever been sunburned, you've experienced the dreaded pain of ...

The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in "Nature ...

In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2, may be ...

A new study might help shed light on sudden infant death syndrome (SIDS) in human babies, which is thought to be associated with dysfunctional airway sensory neurons. The new study might help shed ...

A new study reveals how the uterus senses and responds to pregnancy and birth forces at a molecular level. When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver ...

LA JOLLA, CA—Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing. A new study from Scripps Research scientists shows how ...