Faster motor and cognitive progression of Parkinson disease was found in patients with higher baseline cerebrospinal fluid neurofilament heavy levels. Higher cerebrospinal fluid (CSF) neurofilament ...

Sample size and inclusion of proper control samples are critical factors of study design that can impact the applicability of AD biomarkers to the general public. Some variability is inherent in any ...

Plasma tests for Aβ and phospho-tau may have stolen the show at this year’s Alzheimer’s Association International Conference, held July 14-18 in Los Angeles, but proteomic and synaptic markers were ...

More than any other biofluid, the cerebrospinal fluid is in intimate contact with the brain. What can the thousands of proteins churning within this brain bath tell us about how Alzheimer’s develops, ...

Twenty-four of 25 patients with bacterial meningitis and nine of 11 with CNS viral infection had increased LDH activity in the CSF. The mean levels were 112.8 units per milliliter in bacterial, 193 ...

Expert Rev Proteomics. 2008;5(2):249-262. Similar to the potential ALS biomarkers reported in serum and plasma, many of the CSF-based studies utilize small subject numbers within the sample groups and ...