One small atom can make a big difference in a molecule’s pharmacological properties. Especially if that atom is a nitrogen. Chemists at the University of Oklahoma have now unveiled a new strategy for ...
From left: UChicago chemists Mark Levin, Jisoo Woo, and Tyler Pearson discuss techniques to swap nitrogen atoms in molecules—a change often made by drug discovery chemists. Credit: Julia Driscoll For ...
An unconventional route for modifying pharmaceutically relevant molecules swaps an atom of carbon for one of nitrogen. The resulting derivatives might open up avenues of research in ...