Immunogold EM was employed to compare the distribution of type 1 plasminogen activator inhibitor (PAI-1) on the surface of agonist-activated human umbilical vein endothelial cells (HUVECs) with that ...

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix. The study, led by ...

Matrix metalloproteinases (MMPs) are a family of extracellular, zinc-dependent endopeptidases that have emerged as pivotal regulators of neural plasticity and synaptic function. In the brain, MMPs ...

This review innovatively proposes the use of electrospinning to fabricate electroactive fibrous scaffolds, which mimic the structure of the extracellular matrix while providing electrical activity, ...

Fluorescent microscopy image of a section of mouse brain. Green is a conventional brain ECM marker. Magenta is the new tool developed by the researchers. Between and around the billions of neurons in ...

Extracellular vesicles (EVs), including exosomes, microvesicles, apoptotic bodies, and many other EV subtypes, have emerged ...