Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...
Chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer. Scientists at Université de Montréal's ...
In a recent article published in Proceedings of the National Academy of Sciences, researchers evaluate the potency of antiviral lectins against severe acute respiratory syndrome coronavirus 2 ...
Antibodies that bind to sugars on the surface of cancer cells, rather than to proteins, have not yielded satisfactory results so far due to their low binding affinity. However, scientists at the ...