Researchers at ETH Zurich have identified a compound that targets a previously overlooked protein aggregation mechanism in ...

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...

GSK’s $10.6B buyout caps upside. Deal closure and regulatory approvals remain key risks. Read here for a detailed analysis.

Cellular phase separation may play a previously underappreciated role in regulating kinase activity, offering therapeutic ...

Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and autoimmune disorders. These enzymes have the potential to bind to cellular ...

Few effective treatments exist to treat neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). 1 Existing treatments focus on ...

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

The choice of frontline therapy for a patient with chronic phase chronic myeloid leukemia (CP-CML) can have a profound effect on the long-term clinical outcome. Currently, five tyrosine kinase ...

Medically reviewed by Femi Aremu, PharmD A creatine kinase (CK) test measures the levels of the enzyme in your blood.High levels can be a sign of damage to the muscles, heart, or brain.A doctor may ...