Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...

Human biology is very much like that of other mammals, and yet so very different in areas where it matters. One of these being human neurology, with aspects like the human brain and the somatosensory ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Researchers are no longer just simulating brains in silicon, they are wiring living human neurons into machines and asking them to compute. Tiny clusters of brain cells, grown from stem cells and ...

Human “bodyoids” could reduce animal testing, improve drug development, and alleviate organ shortages. Why do we hear about medical breakthroughs in mice, but rarely see them translate into cures for ...

An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four groundbreaking studies This decade-long project provides the first ...

Mitochondrial diseases are severe, often untreatable, and they leave human cells unable to grow normally without outside help. A new study published in Nature Metabolism now shows that a single gene ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ. These new blood cells are formed in the bone ...