A new study titled "Biomimetic hepatic lobules from three-dimensional imprinted cell sheets" has been led by Prof. Yuanjin Zhao of the Department of Hepatobiliary Surgery, Hepatobiliary Institute, ...

Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...

Close-up of a human liver lobule highlighting GLUL (glutamine synthetase) + liver cells surrounding the central vein (grey), with intensity-based pseudocoloring of CD32b expression showing the highest ...

The paper S. Hoehme et al., “Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration,” PNAS, 107:10371-76, 2010. Free ...

If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first ...

Subtle cellular interactions, especially involving immune cells and lipid metabolism, are crucial in MASH progression. A spatially resolved, multi-omics atlas of MASLD was developed, integrating ...

In biomedical research, so-called organs-on-a-chip, also referred to as microphysiological systems, are becoming increasingly important: by cultivating tissue structures in precisely controlled ...