ascopubs.org

Clinical Utility of Tumor Next-Generation Sequencing Panel Testing to Inform Treatment Decisions for Patients With Advanced Solid Tumors in a Tertiary Care Center

Real-World Impact of an In-House Dihydropyrimidine Dehydrogenase (DPYD) Genotype Test on Fluoropyrimidine Dosing, Toxicities, and Hospitalizations at a Multisite Cancer Center Of the 582 surveys sent, ...
ascopubs.org

Assessment of Functional Status of Human Leukocyte Antigen Class I Genes in Cancer Tissues in the Context of Personalized Neoantigen Peptide Vaccine Immunotherapy

Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...
ITWire

Strand releases Avadis NGS software to enable biologists to analyze next-generation sequence data

Sequencing Simplified. NGS analysis for the rest of us. October 06, 2010, San Francisco, California - Strand Scientific Intelligence, Inc. (Strand) today announced the worldwide release of Avadis NGS, ...
RAPS

FDA Looks to Curate Genetic Databases to Support NGS Validation

Experts met at the US Food and Drug Administration (FDA) today to discuss how curated databases could be used to establish the clinical relevance of genetic variations, and how the agency could use ...
Nanowerk

Next-Generation Sequencing in Genomics and Clinical Research

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...
GEN

A New Proteomics Assay Bridges the Gap between Genotype and Phenotype

Humans have approximately 20,000 human protein-coding genes, and the proteins they express span a concentration range of ~12 logs. Yet only 0.1% of proteins contribute to 99% of the total plasma ...