Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication. Researchers have gained new knowledge of how drugs bind to connexin molecules. These ...