Detailed research over the past decade has shown that that the protein stimulator of interferon genes (STING) is a master regulator of type I interferons and as such plays an essential role in ...
GSK plc has identified cyclic GMP-AMP synthase (MB21D1; cGAS) inhibitors and their prodrugs reported to be useful for the treatment of systemic lupus erythematosus or lupus nephritis.