Delivering a connection-building protein to star-shaped cells in the brain could reverse changes to neural circuits seen in ...

Human karyotype of Down syndrome. Autosomal abnormalities. Trisomy 21. [Rujirat Boonyong/Getty Images] Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule ...

A single missing molecule in the brain is emerging as a powerful new clue to why learning and memory are altered in Down ...

Study provides new evidence that sensory stimulation of gamma-frequency brain rhythm may promote broad-based restorative neurological health response. Studies by a growing number of labs have ...

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and ...

For 10 years, a woman with Down syndrome defied what many scientists believed to be an inevitability. Despite carrying the neuropathological hallmarks of Alzheimer's disease—amyloid beta plaques and ...

A microscopic flaw in the brain’s cellular scaffolding can shape brain size for life.

A missing brain molecule may be disrupting neural wiring in Down syndrome, according to new research. Replacing it in adult mice rewired brain circuits and improved brain flexibility, challenging the ...