Background and aim: The mammalian ductus arteriosus undergoes alterations in its pharmacological responsiveness with advancing gestational age. Cyclic AMP and cyclic GMP are second messengers involved ...
The activation of the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is key for antitumor immunity. However, the development of STING agonist-based strategies in cancer ...
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