Maintaining cells in the quiescent G 0 phase of the cell division cycle is achieved by suppressing the expression of genes required for cell-cycle progression. In the May 10 Science, Hidesato Ogawa ...

Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome.

Recent advances in genomics, genome editing, and imaging technologies have revealed that neural activity can rapidly alter chromatin accessibility, ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

Researchers from the University of Chicago (IL, USA) have reported that unstable, or ‘noisy’, chromatin enables cells to take on different roles in the body. This flexibility can support the immune ...

Beyond their role as the cell’s powerhouses, mitochondria are dynamic signaling hubs that influence immunity, stress responses, and even genetic regulation. The citric acid cycle not only fuels ATP ...