Gastric cancer is a kind of malignant tumor in the world. Emerging studies have proved the regulatory role of nucleoporin 37 in the development of several malignant tumors. However, the potential ...
Cilia are evolutionarily conserved, microtubule-based organelles that project from the surface of most eukaryotic cells and play a central role in sensing ...
The TP63 gene, an important member of the TP53 family, contains two independent promoters that drive the transcription of TAp63 and ΔNp63, respectively. Through alternative splicing, TAp63 and ΔNp63 ...
Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...
New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia ...
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
This article summarizes metabolic reprogramming in prostate cancer (PCa). Early PCa relies more on glycolysis.
How does obesity affect insulin production? Researchers are shining light on new stages of the ERK pathway. Researchers at the Tohoku University Graduate School of Medicine have uncovered a key ...
A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...
A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...
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