Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.

Scientists say this silent bone change could be early sign of leukaemia - Study finds inflammation in bone marrow environment ...

Chronic myeloid leukemia (CML) is a hematopoietic malignancy characterized by BCR-ABL1 gene fusion. The immune microenvironment, implicated in relapse and drug resistance, poses significant challenges ...

Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy. A team of researchers from Colombia Engineering and Irving Institute for Cancer ...

In a recently published study, researchers at Fox Chase Cancer Center revealed for the first time that cancer cells can evade anti-cancer drugs by entering and surviving within bone marrow fibroblasts ...

Bone marrow adipocytes (BMAds) are situated within the bone microenvironment, in close proximity to bone cells, vascular structures, and hematopoietic tissues. The shift of bone marrow stromal/stem ...

Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent an interesting alternative to liver or hepatocyte transplantation to treat liver injuries. Many studies have reported that MSCs can treat ...

Mar. 23 -- FRIDAY, June 15 (HealthDay News) -- Defects in bone marrow can lead to abnormal blood cells that cause precancerous blood diseases in mice, two new studies find. Blood cells are produced in ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

Chronic myeloid leukemia (CML) is a hematopoietic malignancy characterized by BCR-ABL1 gene fusion. The immune microenvironment, implicated in relapse and drug resistance, poses significant challenges ...