A complex cellular process called autophagy is the topic of a major new textbook which encapsulates over 30 years of research in this growing field of study. A complex cellular process called ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders.

Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Memorial Hospital for Cancer and Allied Diseases and the Memorial Sloan Kettering Cancer Center have disclosed 4-aminoquinoline inhibitors of the autophagy-lysosomal pathway (ALP) intended for the ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy-related proteins have been studied in hepatic physiology, the specific ...

Researchers headed by a team at NYU Langone Health have discovered that a feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy. The ...