Review of decades of research highlights how the cellular recycling process known as autophagy is essential for healthy egg ...

This first-in-the-world approach harnesses autophagy to shift DNA repair toward homologous recombination, boosting precision editing efficiency up to threefold. Dr. Hye Jin Nam’s team at the Korea ...

Image Caption: CRISPR-Cas9 library identified XPR1 as a potential gene regulating autophagy. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative ...

Illustration showing how autophagy induction increases the efficiency of precise gene editing. In normal cells, DNA breaks caused by CRISPR–Cas9 are frequently repaired through non-homologous end ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression. The research, conducted by scientists from ...

Not only have researchers identified how a common cellular protein affects aging, but they’ve tweaked the genes that produce it in fruit flies, extending healthy lifespan by 25% to 30%. The discovery ...

Four genetic variants associated with autophagy are linked to increased CLL risk, providing insights into disease biology and potential future screening efforts. The study confirmed associations ...