The modification of the liposomal surface by incorporating negatively charged lipids (e.g., by dicetylphosphate [DCP] incorporation), seems to increase the AM affinity to capture anionic liposomes via ...
Nanomedicine. 2013;8(9):1509-1528. Another important parameter that impacts passive targeting through the EPR effect is the size of the liposomes. The accumulation of liposomes in the tumor strongly ...
LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...