Bills vs 49ers prediction, keys to Sunday Night Football game that may be played in snow
One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be tough to do Sunday night in Buffalo - if they stand any chance of defending their crown because right now they’re in last place in the NFC West and sitting outside the NFC wild-card picture.
Josh Allen Picks, Predictions, and Best Bets for Sunday Night Football
We can project a good rushing performance again, but when it comes to touchdowns, is it James Cook who scores for the Buffalo Bills? He may, and he is the betting favorite, but it’s quarterback Josh Allen who makes the most sense to back.
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The Bills will not have one of their key offensive players for Sunday’s game against the 49ers, though they could get one of their best defensive players back for the matchup.
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