SIRS (systemic inflammatory response syndrome) is a life-threatening medical emergency caused by your body’s overwhelming response to a stressor. This could be things like an infection, trauma or a worsening health condition.
SIRS is a serious condition related to systemic inflammation, organ dysfunction, and organ failure. It is a subset of cytokine storm, in which there is abnormal regulation of various cytokines. [6]
Systemic inflammatory response syndrome (SIRS) is a clinical syndrome characterized by a systemic inflammatory response to an infectious or noninfectious trigger. It involves the release of...
Septic shock is defined by cardiovascular dysfunction, marked by hypotension for age, lactate >5 mmol/L, or need for vasoactive support. In summary, almost all septic patients exhibit SIRS, but not all patients with SIRS are septic.
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Objectively, SIRS is defined by the presence of any 2 of the following criteria: Sepsis, Septic Shock, and Multiple Organ Dysfunction Syndrome. SIRS with a suspected infectious source is termed sepsis. Culture confirmation is not required early in diagnosis.
Systemic Inflammatory Response Syndrome (SIRS) is a critical medical condition marked by a dysregulated systemic inflammatory response that transcends the localized battleground of infection or injury.